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To clinical microbiologists, laboratory technologists, and infectious disease specialists for 40 years, enabling them to accurately detect clinically significant bacteria, viruses, fungi, and parasites. This 10th edition represents the collaborative efforts of 22 editors and more than 260 authors from around the world, all experienced researchers and practitioners in medical and diagnostic microbiology. Together, they have brought the manual fully up to date, producing two volumes, nine sections, and 149 chapters that is filled with the latest research findings, infectious agents, methods, practices, and safety guidelines. This 10th edition continues to set the standard for state-of-the-science laboratory practice. It begins with a section dedicated to core diagnostic strategies and topics. Next, it helps readers understand the underlying mechanisms of both common and emerging infectious agents and diseases. With its careful step-by-step guidance, the Manual enables readers to correctly perform the appropriate diagnostic, therapeutic, and susceptibility tests and then interpret the results. Rounding out its coverage, the Manual addresses the taxonomy, biology, epidemiology, transmission, and clinical significance of almost all microorganisms that cause disease in humans. Fully updated and revised, this edition encapsulates the knowledge, practices, and procedures of the field, enabling readers to accurately detect pathogens and diagnose infectious disease.

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"Viruses: Biology, Applications, and Control is a concise textbook for advanced undergraduate and graduate students and is an updated and expanded version of the Second Edition of David Harper's Molecular Virology. Focusing on key mechanisms and developments, Viruses presents many recent scientific advances, including virus evolution, emerging infections, virus extinction, control of infections, antiviral drugs, gene therapy, bacteriophage therapy, and diagnostics. The first chapters introduce the reader to the structure and nature of viruses, including their classification and evolution. As viruses cause widespread and serious disease, the ensuing chapters explain how they interact with the immune system and the different ways we try to defeat them: vaccines, antiviral drugs, and immunotherapy. Laboratory methods for viral detection and laboratory diagnosis are also covered. While viruses do cause disease, many do not, and their special biology means they can have beneficial uses and this aspect of viruses is included. One of the most interesting areas in virology, given extensive coverage here, is how new viruses emerge and establish themselves. Viruses: Biology, Applications, and Control is a rigorous treatment of the molecular side of virology and its conceptual approach makes it an essential text for students and non-specialists"--Provided by publisher.

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